Image: courtesy of P. Lenart et al., MPI for Biophysical Chemistry, Göttingen, Germany.

Discover the ZEISS LSM 9 Family with Airyscan 2

Your next generation confocals for fast and gentle Multiplex imaging

Discover the LSM 9 family for confocal 4D imaging with high sensitivity and spectral flexibility. Add Airyscan 2 with its new Multiplex mode to profit from smart detection schemes and parallel pixel acquisition. Gently image dynamic processes in larger fields of view in superresolution and with acquisition times shorter than ever before. Or image your fixed samples with higher throughput and less bleaching.

Your confocal 4D imaging with the new LSM 9 family and Airyscan 2 benefits from:

Faster, better data: the new Multiplex mode for parallel pixel acquisition acquires up to 8 superresolution image lines with a high signal-to-noise ratio (SNR) in a single sweep
Increased productivity: ZEN imaging software with Smart Setup, Sample Navigator, and Direct Processing makes your work more efficient
More sensitivity: a light efficient beam path and Airyscan 2 offer a unique combination of gentle superresolution, high SNR, and spectral flexibility

Cells, widefield image (left) and Lattice SIM image (right)

Multiplex Mode

Get more image data in less time

The new Multiplex mode uses knowledge about the shape of the excitation laser spot and the location of single area detector elements to extract more spatial information, even during parallel pixel readout. This allows to take bigger steps when sweeping the excitation laser over the field of view, improving achievable acquisition speeds. Airyscan 2 in Multiplex mode can acquire up to eight superresolution image lines with high SNR.

Study the motility of vesicles and organelles, follow fast processes such as calcium waves, muscle contractions, blood flow, cilia beating while keeping structural information, or image large fields of view at high volume rate to capture developmental processes.

Watch the Multiplex mode Animation Trailer

	Airyscan SR	Multiplex SR-2Y	Multiplex CO-2Y	Multiplex SR-4Y	Multiplex SR-8Y	Multiplex CO-8Y
Parallelization	1	2	2	4	8	8
Lateral resolution (nm)	120/120	140/140	Confocal or better	140/140	120/160	Confocal or better
Antibody labeling, fine structures	++++++	+++++	++	+++++	++++	++
Antibody labeling, tiling	++	+++	+++	+++++	++++++	++++
Live cell imaging	++	++	++++	+++	+++++	++++++
LSM 900 / LSM 980	✔ / ✔	✔ / -	✔ / -	✔ / ✔	- / ✔	- / ✔

SR = Superresolution, CO = Confocal, Y = Parallelization in Y

ZEN Imaging Software

New software helpers save time and ensure reproducible results

Use the familiar interface of ZEN imaging software to drive the LSM 9 family. It’s easy to set up experiments and a wealth of software helpers is at your command. You can concentrate on always getting the best image data from your samples.

Smart Setup lets you select your dyes and automatically applies all necessary imaging settings for all LSM imaging modalities. Save imaging configurations or whole experiments to reproduce settings quickly, or extract and load imaging settings from existing images.

The new Sample Navigator lets you quickly acquire an overview image of your whole sample to easily find and image regions of interest. And with ZEN Connect, exchange and overlay image data from multiple image acquisition systems.

Use your time during the acquisition efficiently. Direct Processing enables parallel acquisition and data processing, including analysis and storage on a second computer.

ZEISS LSM 900 and LSM 980

Your compact workhorse & the most flexible confocal research platform

Your LSM 900 is packed with innovative solutions for producing the best quality in confocal live cell imaging. The elegant beam path is designed for high spectral flexibility and sensitivity. With its small footprint and reduced complexity, you save valuable lab space and minimize time needed for user-training. Learn more

For your most challenging samples, LSM 980 pushes sensitivity and superresolution imaging even further. You get a light efficient beam path with up to 34 simultaneous channels for full spectral flexibility. Stretch the excitation laser spot to image eight lines in parallel (Multiplex SR-8Y / CO-8Y) and use this speed advantage for ultrafast time series of single slices, rapid tiling of large areas, or fast volumetric time-lapse imaging. Learn more

Multiplex Mode

White Paper

How does the Multiplex mode work? Understand how this new method can advance your research in this White Paper.

Download Multiplex White Paper

ZEISS LSM 900

Product Brochure

Need all the information about LSM 900 in one place? Download the Product Brochure below and go into the details.

Download LSM 900 Product Brochure

ZEISS LSM 980

Product Brochure

Do you want to know more about LSM 980? This Product Broschure includes all its details. Download it below.

Download LSM 980 Product Brochure

Get in contact with us

Speak to our confocal microscopy experts about your challenges

Get in touch with us to get to know how the LSM 9 family benefits your specific research challenges or facility, book a demo at our customer center, or get a quote. We are looking forward to hearing from you.