Expanding insights into the Retinopathy of Prematurity (ROP)
LVPEI Atlas of Retinopathy of Prematurity and other Neonatal Diseases

Expanding insights into the Retinopathy of Prematurity (ROP)

Unveiling stories of ROP with ZEISS CLARUS 700

The story of ROP has never been captured before with such pristine clarity. For the very first time we welcome you to the world of ROP in true colours

Dr. Akash Belenje

MS, Vitreoretinal Faculty, L V Prasad Eye Institute, Hyderabad

Retinopathy of Prematurity (ROP)

Retinopathy of Prematurity (ROP)

Retinopathy of Prematurity (ROP) is an eye disease that could happen in babies born early (premature) or who often, though not always, weigh less than 2000 grams at birth. ROP occurs when abnormal blood vessels grow in the retina. 

ROP is an emerging epidemic of the 21st century and is attributed to increased premature deliveries, often associated with teenage pregnancies, malnourished mothers, assisted fertilization, and delayed pregnancies.

ROP is a rapidly progressive, time-bound disease that is not present at birth but develops over a few weeks. The condition is characterised by the development of abnormally proliferating new vessels in the retina, leading to tractional retinal detachment and vision loss. ROP typically starts 3 to 4 weeks after birth, providing a window for screening and initiating treatment at the right time before it progresses in the next few weeks to a stage of retinal detachment that results in incurable blindness. Timely screening of all premature-born at risk babies and timely intervention with adequate follow-up care can prevent the sight-threatening consequences of ROP.

Unedited Real time image capture by ZEISS CLARUS 700

Non-contact wide-field fundus imaging

Imaging the retina is important in Retinopathy of Prematurity (ROP) not only for documentation, follow-up, teleconsultation, sharing with parents and for teaching students, but also from medico-legal perspectives.

Fundus photography is all about the 'colour'. While a high resolution and widefield of view are a pre-requisite to get all the information, the true colours are an important component for accurate interpretation and diagnosis. Most of the dedicated neonatal fundus cameras are 'contact' systems and the 'pseudo-colours' in some cameras can camouflage the true nature of the disease.

The ZEISS CLARUS 700 imaging system lends itself readily to neonatal retinal imaging. The fast rate of image acquisistion and non-contact nature are comfortable and safe for the baby. The ZEISS CLARUS 700 which uses true colour reflectance imaging with high resolution and a non-contact approach, hence has a great potential for fundus photography of newborn babies in addition to its current usefulness in adult retinal diseases.


A glimpse into the world of ROP

Anant Bajaj Retina Institute diagnostic team at LVPEI under the leadership of Dr. Akash Belenje and Mr. R Ugandhar Reddy have demonstrated in this atlas something unique and is published for the very first time. The atlas contains 100 ROP images of varying disease severity and in different clinical situations. The true colour reflectance images with high resolution provide a wonderful opportunity to see the entire spectrum of ROP presentations, follow-up, pre and post treatment and its natural history.

"The atlas showcasing true colour fundus imaging of ROP babies fills the gap of neonatal fundus photography in our routine retina clinics without need for additional equipment, space, or human resource

Dr. Subhadra Jalali

Network Director, Newborn Eye Health Alliance (NEHA), Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad



Color. Clarity. Complete.

CLARUS 700 from ZEISS was designed as a comprehensive ultra-widefield retinal camera for eye care specialists to capture ultra-widefield images in true color, with unsurpassed image quality and a complete suite of modalities including fluorescein angiography.

  • Unsurpassed color and clarity
  • High-resolution FA
  • Advanced imaging features

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